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• Binding: Mass Market Paperback

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[N637.Ebook] PDF Download Drugs: From Discovery to Approval, by Rick Ng

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"Concise and easy to read, the book quickly introduces basic concepts, then moves on to discuss target selection and the drug discovery process for both small and large molecular drugs."
—Doody's Reviews, May 2009

"The second edition of a book that offers a user-friendly step-by-step introduction to all the key processes involved in bringing a drug to the market, including the performance of preclinical trials."
—Chemistry World, February 2009

The new edition of this best-selling book continues to offer a user-friendly, step-by-step introduction to all the key processes involved in bringing a drug to the market, including the performance of pre-clinical studies, the conduct of human clinical trials, regulatory controls, and even the manufacturing processes for pharmaceutical products. Concise and easy to read, the book quickly introduces basic concepts, then moves on to discuss target selection and the drug discovery process for both small and large molecular drugs.

This second edition features many key enhancements, including Key Points, Chapter Summary, and Review Questions in each chapter, Answers to Review Questions provided in a book-end appendix, and one or two carefully selected "mini" case studies in each chapter.

Richly illustrated throughout with over ninety figures and tables, this important book also includes helpful listings of current FDA and European guidelines and a special section on regulatory authority and processes in China. It is an indispensable resource for pharmaceutical industry and academic researchers, pharmaceutical managers and executives, healthcare clinicians, policymakers, regulators, and lobbyists with an interest in drug development. It is also an excellent textbook for students in pharmacy, science, and medicine courses.

• Sales Rank: #644876 in Books
• Published on: 2008-12-03
• Original language: English
• Number of items: 1
• Dimensions: 9.60" h x 1.20" w x 6.50" l, 1.70 pounds
• Binding: Hardcover
• 480 pages

Review
"Concise and easy to read, the book quickly introduces basic concepts, then moves on to discuss target selection and the drug discovery process for both small and large molecular drugs." (Doody's Reviews, May 2009)

"This textbook provides the reader with a high-level overview of the drug discovery process and the regulatory challenges facing the journey from drug molecule to marketplace." (The Pharmaceutical Journal, March 2009)

"The second edition of a book that offers a user-friendly step-by-step introduction to all the key processes involved in bringing a drug to the market, including the performance of preclinical trials." (Chemistry World, February 2009)

From the Back Cover
Praise for the First Edition

"A concise, yet comprehensive, survey of the entire drug development process."
—Journal of Chemical Technology and Biotechnology

The new edition of this bestselling book continues to offer a user-friendly, step-by-step introduction to all the key processes involved in bringing a drug to the market, including the performance of preclinical studies, the conduct of human clinical trials, regulatory controls, and even the manufacturing processes for pharmaceutical products. Concise and easy to read, the book quickly introduces basic concepts, then moves on to discuss target selection and the drug discovery process for both small and large molecular drugs.

This Second Edition features many key enhancements, including Key Points, Chapter Summary, and Review Questions in each chapter; Answers to Review Questions provided in an appendix; and carefully selected "mini" case studies in each chapter.

Richly illustrated throughout with over ninety figures and tables, this important new edition also includes helpful listings of current FDA and European guidelines and a special section on regulatory authority and processes in China. It is an indispensable resource for pharmaceutical industry and academic researchers, pharmaceutical managers and executives, healthcare clinicians, policymakers, regulators, and lobbyists with an interest in drug development. It is also an excellent textbook for students in pharmacy, science, and medicine courses.

About the Author
Rick Ng, PhD, has worked for more than twenty-five years in senior management positions in the private sector pharmaceutical industry. He is currently a director at a biopharmaceutical manufacturing facility in Singapore. He has provided technical training for graduate and postgraduate personnel.

Most helpful customer reviews

1 of 1 people found the following review helpful.
Helped me understand the full Drug Discovery landscape and gain overall perpective
By Pankaj Shukla
I work as an account manager in the Life Sciences vertical of an ITES organisation. I have been in the system for quite some time and had gained understanding of some of the key Pharmaceutical business fucntion.

This book particularly helped me to understand the full landscape and gain overall perpective. I would recommend this to anyone who has some or no business function knowledge and is wanting to consolidate. I would also recommend you to note down the points that are of interest to you and weave them in your own Pharma story.

I have now picked up Manual of Drug Safety And Pharmacovigilance. I am hoping this book would be as interesting as the earlier one.

0 of 0 people found the following review helpful.
great book
By M. Zimmermann
I have a chem/biochem background and am about to finish my PhD. This book was great help for preparing for interviews in the pharmaceutical industry. Especially if you do not know anything about drug development, clinical trials and GxP regulations it is worth the money!

0 of 0 people found the following review helpful.
Informative
By Dennis Trent
A solid reference book for those not professional in regulatory affairs. Clear and objective. Needs revision.

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[W773.Ebook] Get Free Ebook Concepts in Submarine Design (Cambridge Ocean Technology Series), by Roy Burcher, Louis J. Rydill

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This book shows how the engineering and architectural aspects of submarine design relate to each other, and describes the operational performance required of a vessel. The authors explain concepts of hydrodynamics, structure, powering and dynamics, in addition to architectural considerations that bear on the submarine design process. They pay particular attention to the interplay among these aspects of design, and devote a final chapter to the generation of the concept design for the submarine as a whole. Submarine design makes extensive use of computers, and the authors give examples of algorithms used in concept design. They provide engineering insight as well as an understanding of the intricacies of the submarine design process. The book will serve as a text for students and as a reference manual for practicing engineers and designers in marine and naval engineering.

• Sales Rank: #5283945 in Books
• Published on: 1994-01-28
• Original language: English
• Dimensions: 8.98" h x .79" w x 5.98" l,
• Binding: Hardcover
• 314 pages

Review
"Part of Cambridge University Press's Ocean Technology Series,

this book explores the many engineering and architectural aspects of submarine design. Particular attention is given to the interplay between aspects of hydrodynamics, structure and propulsion, and many examples of concept design algorithms are provided. This book will serve as a text for students and as a reference manual for practicing engineers, naval architects, and designers." Proceedings, a publication of the United States Naval Institute, July 1994

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0 of 0 people found the following review helpful.
Five Stars
By Amazon Customer
Excelent

1 of 2 people found the following review helpful.
Concepts in Submarine Design (Cambridge Ocean Technology Series)
By Ellen Glynn
Was concerned about the condition of a used book. However it was in mint condition.
As for the content my son is using it as a research book for a submarine project at school.
The teacher recommends it.

17 of 19 people found the following review helpful.
Good technical look at sub design
By Tugboat
The guy who didn't like this book must not have read anything other than the back cover. I used this book when studying for engineering quals on the USS Albuquerque, and it was of great assistance to me. It does have some flaws, which would mainly be an issue for people with no exposure to naval engineering. That being said, it's readable enough that anyone can learn quite a bit about submarine design. The discussions on hull shape,drag, and propulsion alone are worth the price.

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[E266.Ebook] Download PDF TURNING OUT THE LIGHTS: Concussions, Spectacle and the NHL, by David Gowdey

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In 1998 Steve Bocking suffered his second concussion in two years playing hockey. His father was a surgeon who had seen enough. He started a campaign to change the rules, and won in 2011 when Hockey Canada banned all head shots. But the NHL still refuses to listen. When did the game change? What are the dangers of concussions? Why does the world's top hockey league continue to ignore the evidence?

• Sales Rank: #2190015 in eBooks
• Published on: 2013-11-15
• Released on: 2013-11-15
• Format: Kindle eBook

Most helpful customer reviews

1 of 1 people found the following review helpful.
Th Human Brain Versus the NHL
By Jeff Walker
This is a book that should be stocked not only by every bookstore that puts hockey books on its shelves but by any sporting goods store that sells hockey equipment. I wish the author had plugged away at finding a major publisher because this book deserves one. It's both exceptionally well written and exceptionally timely.

The book quotes the great center for the Montreal Canadiens Jean Beliveau: "You can play this game perfectly and never intentionally hurt anybody." Therein lies the deterioration of hockey civility, irrespective of today's higher calibre of play. Today's NHL features all kinds of players whose raison d'etre is to hurt opposing players so badly that they'll not only be out of the game, they'll be out like a light and even out for the rest of the season. And sometimes it's a Sid Crosby or a Wayne Gretsky lying on the ce. That mentality was foreign to the old NHL. It did not glorify players whose only skills were fighting and brutal body checking. Now, as even former big bad Bruin turned hockey commentator Mike Milbury puts it, "There's six or seven players every shift now who don't care about the puck." In the 1960s, such a statement would be unintelligible. How could ANY hockey player not care about the puck? Sadly, it wouldn't surprise any fan today. Gowdey traces the evolution of this mentality and how an increasing incidence of concussions has accompanied it. He is not to be accused of wanting to convert the NHL to a gentler European style of play. He mostly just wants to reduce NHL barbarism to a bare minimum. The whole idea that the NHL should tolerate a much higher rate of brain injury than is inevitable is appalling. (Oh, sorry, it's just the brain. I thought we were talking about an important human organ.)

Gowdey makes clear that the problem is not illegal hits. The problem is mostly legal hits that should be illegal. Rule 48 was supposed to eliminate nasty head shots, but it can't work because it's couched in too many qualifiers. Skating lawyers, not referees, would be required to interpret and apply this rule effectively. Head shots should simply not be permitted--period, no qualifiers. And why not rehabilitate old rules that are seldom invoked anymore such as those penalizing charging or deliberate intent to injure?

The game is too fast and the players too big to avoid unacceptable rates of concussion under current rules. What is particularly horrible is that the vast majority of concussions happen without the drama of a player getting knocked out, which at least alerts everyone to the seriousness of what just took place. And the effects of minor concussions are cumulative. It's an insidious problem.

How can players with real hockey skills function at anywhere near their best when they know that they may very well be clobbered by the on-ice equivalent of a Brinks armored truck after they make a pass, even seconds later? So many bona fide hockey stars have had their seasons punctuated with injuries that were very much intended by goons or have had their careers thereby shortened. The excessive violence hurts and demeans the game as a spectacle. Apart from the pleasure of seeing an expansion team win the Stanley Cup mostly with sensational goaltending, who wants to revive the likes of Philadelphia's Broad Street bullies, as opposed to the likes of real hockey-playing teams such as the late 1970s Montreal Candiens?

Gowdey's arguments are more sophisticated and more charitable to Don Cherry types than what I've extracted above in broad strokes. And he embeds them within historical developments that many fans are probably not aware of. Most fans, unlike myself, continue to watch the game despite the barabarism. Count Gowdey amongst the optimists who continue to watch, partly in the hope of identifying what needs to be changed and then arguing passionately for such changes. Gowdey's passion for the game of hockey comes through loud and clear, and that's why even defenders of the status quo should listen up. Moreover: it's not a long book. It can easily be read over a weekend.

1 of 1 people found the following review helpful.
NHL....Wake Up!!!
By Nemchinov13
The author takes a nostalgic look at hockey history and winds it through to the present. Along the way, he discusses the evolution of checking and why concussions have become so much more commonplace. The science of concussions is presented in an easy to understand way and the book doesn't get bogged down with medical jargon. The book is presented in such a way that the point is made, but not at the author's risk of coming across as a one who longs for the days of old. A super read for any hockey fan, athlete or parent.

1 of 1 people found the following review helpful.
A timely "must read" for coaches, players and parents.
By Annie Spiegelman
David Gowdey’s newest book, “Turning Out The Lights” combines hockey history, statistical facts, and the latest medical research on the most feared and least understood of all sports injuries: concussions. This is a timely “must read” for all coaches, players, and parents whose kids aspire to play contact sports. Bravo, David.

William Buzbuzian, Doctor of Chiropractic
[...]

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The student solutions manual provides worked-out solutions to the odd-numbered problems in the text.

• Sales Rank: #2409521 in Books
• Brand: Brand: Cengage Learning
• Published on: 2005-01-17
• Original language: English
• Number of items: 1
• Dimensions: 11.00" h x 8.50" w x 1.00" l,
• Binding: Paperback
• 480 pages

Features

• Used Book in Good Condition

About the Author
Earl Swokowski authored multiple editions of numerous successful textbooks, including CALCULUS; CALCULUS OF A SINGLE VARIABLE; FUNDAMENTALS OF COLLEGE ALGEBRA; and PRECALCULUS: FUNCTIONS AND GRAPHS, all published by Cengage Learning Brooks/Cole.

Jeffery A. Cole has been teaching mathematics and computer science at Anoka-Ramsey Community College since fall 1981. He started working on the Swokowski series of precalculus texts in 1985 as an ancillary author, and has been a co-author since 1991. His contribution to the Swokowski texts also includes joining the revision team of the calculus text in 1989.

Most helpful customer reviews

4 of 4 people found the following review helpful.
A Must Have book!
By redkcir
I am an adult returning to collage at 59. As you may imagine and higher math training I received has long been forgotten. The fast pace teaching was leaving me without a clue as to what I needed to do in this course. While the text book had answers to the odd questions, with out an explanation of how they were obtained they weren't much use. When I went to school way back then we didn't study algebra, so I wasn't up to speed in the subject as were the younger students just out of high school. This companion to the text book has the odd answers and how they were done, along with explanations. If you are having a hard time you need this book.

0 of 0 people found the following review helpful.
Wouldn't take pre-calc without it
By Patrick L
All of the odd problems worked out, step by step.

The formatting isn't pretty, but I don't care.

I used this book (11th edition), with my 12th edition text book. Out of my assigned homework, I found only two problems that were different between the two.

3 of 3 people found the following review helpful.
Fair
By Algebra Woes
The solutions manual is helpful yet can be confusing bcause the manual teaches you the long way which could sometimes prove to be confusing. It is best to understand the formulas first and then use the manual as a cross check to verify that the final solution is correct.

See all 3 customer reviews...

Student Solutions Manual for Swokowski/Cole's Algebra and Trigonometry with Analytic Geometry, 11th, by Earl W. Swokowski, Jeffery A. Cole PDF
Student Solutions Manual for Swokowski/Cole's Algebra and Trigonometry with Analytic Geometry, 11th, by Earl W. Swokowski, Jeffery A. Cole EPub
Student Solutions Manual for Swokowski/Cole's Algebra and Trigonometry with Analytic Geometry, 11th, by Earl W. Swokowski, Jeffery A. Cole Doc
Student Solutions Manual for Swokowski/Cole's Algebra and Trigonometry with Analytic Geometry, 11th, by Earl W. Swokowski, Jeffery A. Cole iBooks
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Student Solutions Manual for Swokowski/Cole's Algebra and Trigonometry with Analytic Geometry, 11th, by Earl W. Swokowski, Jeffery A. Cole PDF

Student Solutions Manual for Swokowski/Cole's Algebra and Trigonometry with Analytic Geometry, 11th, by Earl W. Swokowski, Jeffery A. Cole PDF

Student Solutions Manual for Swokowski/Cole's Algebra and Trigonometry with Analytic Geometry, 11th, by Earl W. Swokowski, Jeffery A. Cole PDF

Student Solutions Manual for Swokowski/Cole's Algebra and Trigonometry with Analytic Geometry, 11th, by Earl W. Swokowski, Jeffery A. Cole PDF

[Y354.Ebook] Ebook 500 ACT Math Questions to Know

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500 Ways to Achieve Your Highest Score

We want you to succeed on the Math sections of the ACT. That's why we've selected these 500 questions to help you study more effectively, use your preparation time wisely, and get your best score. These questions are similar to the ones you'll find on the ACT, so you will know what to expect on test day. Each question includes a concise, easy-to-follow explanation in the answer key for your full understanding of the concepts. Whether you have been studying all year or are doing a last-minute review, McGraw-Hill's 500 ACT Math Questions to Know by Test Day will help you achieve the high score you desire.

Sharpen your subject knowledge, and build your test-taking confidence with:

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• Full explanations for each question in the answer key
• A format parallel to that of the ACT exam

• Sales Rank: #85548 in Books
• Published on: 2013-11-05
• Released on: 2013-11-05
• Original language: English
• Number of items: 1
• Dimensions: 9.00" h x .47" w x 6.00" l, .64 pounds
• Binding: Paperback
• 208 pages

About the Author

Cynthia Johnson has more than 20 years experience in writing and editing test-prep guides for America’s leading educational publishers.

Most helpful customer reviews

3 of 3 people found the following review helpful.
AUTHOR NEEDS BASIC MATH LESSONS.
By Andy
The writer claims that she is professor of Math, but a quick review of the book reveals author needs basic Math lessons. For example, Question #292, shortest side of an isosceles triangle is 10 m, and the longest side is 20 m. Madam, how is that possible?. Do you know that sum of two sides of a triangle has to be greater than the third?
Also, same mistake is repeated in Question #300: The sides of a triangle have lengths of 3, 3 and 12 meters. Again, YOU CANNOT FORM A TRIANGLE WITH SIDES 3, 3 and 12. This is very basic math that sum of two sides of a triangle have to be greater than the third. FAIL GRADE FOR YOU PROFESSOR.

2 of 2 people found the following review helpful.
and this book is great for tutors because it is simply a list of ...
By Jeff
I am a math tutor, and this book is great for tutors because it is simply a list of problems, with brief answers at the back. It has a great organization, so you can point your student to the correct section and have a many problems for them to do. Even better would have been if this book had a diagnostic test which gave the students' feedback aligned with the way they have subdivided the topic and a brief paragraph (or two) describing the skills each chapter teaches (e.g., What does the chapter "Numbers" cover? What about the chapter "Proportions"? etc.)

I also note that there is no trigonometry chapter and, as is usual for books of this type, there is no index.

2 of 2 people found the following review helpful.
It's nice!
By Emily Tsai
This is a good review. It's different from other ACT practice test books. You can find out what kind of problem you have in different topics. And they also provide some fresh questions you will not see in the other practice test book.

See all 17 customer reviews...

500 ACT Math Questions to Know PDF
500 ACT Math Questions to Know EPub
500 ACT Math Questions to Know Doc
500 ACT Math Questions to Know iBooks
500 ACT Math Questions to Know rtf
500 ACT Math Questions to Know Mobipocket
500 ACT Math Questions to Know Kindle

500 ACT Math Questions to Know PDF

500 ACT Math Questions to Know PDF

500 ACT Math Questions to Know PDF

500 ACT Math Questions to Know PDF